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Wegovy patients begin at 0.25 mg weekly injection, escalate through several steps, and reach a maximum dose of 2.4 mg weekly for weight management

Dependiendo de la estructura del ligando, se modulan las vas de sealizacin intracelular hacia la generacin de AMP cclico, cascada de activacin de quinasas (ERK) y reclutamiento de beta arrestina-1 que condiciona el efecto biolgico y la desensibilizacin del receptor de GLP-14

Phase 3 doses are titrated up gradually to a maximum of 12 mg per week

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