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Wegovy HD carries the same boxed warning as the lower doses for thyroid C-cell tumors

It also provides multiple health benefits, including: Improved insulin sensitivity Reduced risk factors for cardiovascular disease Lower blood pressure levels Improved liver function in cases of fatty liver disease These broader health benefits make tirzepatide an appealing choice for those seeking health improvements alongside weight loss

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Reporting suspected side effects is a vital part of medicines safety in the UK, and this principle applies equally to investigational treatments used within clinical trials

Preclinical studies indicate that metformin promotes M2 macrophage polarization through STAT6 activation, which facilitates tissue repair and attenuates TGF-1-mediated renal fibrosis (109)