If constipation persists despite these measures, over-the-counter laxatives like polyethylene glycol (Miralax) can be used short-term
The SELECT trial (Lincoff et al., NEJM 2023, NCT03574597) extended Semaglutide research to cardiovascular outcomes in 17,604 adults with obesity and prior cardiovascular disease (no T2D) over a mean ~34-month follow-up
Healthcare professionals should provide comprehensive counselling about realistic expectations, potential side effects, and the importance of lifestyle modifications alongside pharmacotherapy for optimal outcomes in cardiometabolic health
Read AD, Bentley RE, Archer SL, Dunham-Snary KJ (2021) Mitochondrial ironsulfur clusters: Structure, function, and an emerging role in vascular biology
Another thing it does is it slows food processing through your intestines and helps you feel fuller longer