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Depressive episodes are in many ways more challenging for patients and clinicians than other bipolar disorder episodes, including manic or mixed mood episodes: 1

In addition, many available studies rely on relatively small cohorts or cross-sectional designs, limiting the ability to establish causal relationships between gut dysbiosis and PCOS development ( 7.1 Future implications Despite the growing body of evidence linking gut microbiome dysbiosis to the pathophysiology of PCOS, several important questions remain unresolved

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