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276 The commonly used hypoglycemic drug metformin is an additional AMPK activator that can inhibit the release of inflammatory cytokines by activating the AMPK pathway, thus exerting an obvious anti-inflammatory effect

Retrieved from DrugBank

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References: Blundell, J

While GLP-1 RAs are known to help control blood sugar and support weight loss, this study is the first to comprehensively rank these drugs against each other, as well as against traditional diabetes treatments such as insulin and metformin