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This underscores the importance of seeking professional guidance when considering such treatments

This was associated with substantive mobility of the RAMP2 linker and TM helix, which had weaker interaction with the CTR TM bundle compared to RAMP1 and RAMP3 in AMY 1 R and AMY 3 R complexes

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Future work should further deepen research into cell death mechanisms (especially pyroptosis and ferroptosis) and inflammatory/oxidative stress pathways, refine preclinical models to better mimic human conditions, and conduct large-scale clinical cohort studies to validate potential therapies

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