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"I'd say maybe only a handful of people at most in the last 10 years have I ever actually thought would benefit from B12 injections." As to why some physicians would be needlessly prescribing B12 shots, he said, "It may be just habit

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[4] What to do about it: Leave it alone unless its larger than 1 cm or painful, then see a provider for possible aspiration

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There are more than fifty variants of MTHFR