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At therapeutic doses, about 5070% of APAP is glucoronidated [mainly via UGT1A1 and/or UGT1A6 (McGill and Jaeschke 2013)] and 2535% is sulphated via enzymes of the SULT1 family to be excreted in urine (Coen 2015)

In vitro and in vivo efficacy of azd3965 and alpha-cyano-4-hydroxycinnamic acid in the murine 4t1 breast tumor model

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doi: 10.3389/fendo.2021.678055 Received 08 March 2021 Accepted 15 April 2021 Published 10 May 2021 Volume 12 - 2021 Edited by Peter Flatt, Ulster University, United Kingdom Reviewed by Jonathan Campbell, Duke University, United States