They can be aggravated by certain medications, such as NSAIDs
What many people don't realize is just how strongly sleep apnea and body weight are connected: Approximately 40% of people with obesity have significant sleep apnea Around 70% of sleep apnea patients are classified as obese A mere 10% increase in body weight can increase your sleep apnea risk sixfold Conversely, losing just 10% of your body weight can dramatically decrease sleep apnea severity This strong relationship explains why weight loss has always been recommended for sleep apnea management

pigmentation is nonmelanocytic) Drug reactions (hydroxyurea, antiretrovirals, antimalarials, metals) Endocrine disease (Addison disease, Cushing syndrome) Nonmelanocytic tumours (squamous cell carcinoma in situ, onychomatricoma, myxoid cyst, viral warts) Melanocytic naevus of nail matrix Lentigo / benign melanocytic hyperplasia Malignant melanoma Nails grow slowly, taking months to reach the distal edge, and longitudinal melanonychia reflects melanin deposition rather than the site of its production
It's best to consult your doctor
Will it have a significant impact on DHT or E2