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For simulation of typical profiles at steady state, mean parameter values are shown in Table 2 for the subset of the clinical pharmacology population who used the recommended dosing conditions for oral semaglutide ( N = 209 healthy subjects, N = 55 subjects with T2D)
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A few participants with a BMI above 27 kg/m participated, but only if they had an additional weight-related health issue, such as hypertension or hyperlipidemia
This mechanistic advantage potentially offers more robust weight reduction results, making it a highly anticipated tool in fighting obesity
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