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Vitamin B12 is an essential nutrient that plays a role in energy production, and low levels can contribute to fatigue

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155 Additionally, targeting bile acid metabolism, such as through bile acid sequestrants and farnesoid X receptor agonists, has shown promise in preclinical models by reducing bile acid accumulation and hepatotoxicity

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J Soil Sci Plant Nutr 22:121139 Altaf MA, Shahid R, Ren MX, Naz S, Altaf MM, Khan LU, Lal MK, Tiwari RK, Shakoor A (2022) Melatonin mitigates cadmium toxicity by promoting root architecture and mineral homeostasis of tomato genotypes