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Prevnar family (pneumococcal 13-valent conjugate vaccine) Disease area(s): Vaccines/infectious diseases Manufacturer(s): Pfizer 2024 Sales (USD): $6.41 billion Why it sold so well: In 2024, Pfizers Prevnar family of pneumococcal vaccines generated $6.4 billion in global revenue, accounting for 10% of the companys total revenue and ranking as its second-highest-selling product after Eliquis