Some GLP-1 RAs (albiglutide, efpeglenatide, dulaglutide, liraglutide, and once-weekly semaglutide) reduce the risk of major adverse cardiovascular events (MACE) in people with type 2 diabetes (T2D) with established CVD or at high risk of CVD [19,20,21,22,23]
Staying well-hydrated is the most important factor in reducing this risk
00:16:22 Vickie Danaher For now, wed also want to suggest oral semaglutide in patients who have cardiovascular disease, since semaglutide has the benefit of reducing the risk of MACE or major adverse cardiovascular events like CV death, heart attack, or stroke, but orforglipron doesnt yet have this indication
But since peptide coupling agents are described as immune sensitizers, it stands to reason that the risk even if its small exists for everyone.18 Copper peptide uglies Anecdotal reports suggest that some people may experience worsened skin aging, instead of anti-aging, after using products with GHK-Cu, a rare concern dubbed copper peptide uglies. While this isnt necessarily a safety issue, it is a (again, rare) potential negative effect of using copper peptide products
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