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doi: 10.3389/fnins.2023.1087788 147 HendersonCWijetungeLKinoshitaMNShumwayMHammondRSPostmaFRet al

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10.1073/pnas.1711235114 70 CersosimoM

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GLP-1R expression in the immune system GLP-1 medicines regulate inflammation partly by directly modulating immune cells, although GLP-1R expression is typically low in lymphoid organs (Figure 1) (26)

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Enhanced Detoxification Support: The reduced L-glutathione in this formula directly supports liver detoxification pathways, helping the body eliminate toxins, heavy metals, and environmental pollutants more effectively

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The supply pathway involves the export of GSH from astrocytes via the multidrugresistance protein 1 (Mrp1), extracellular processing of GSH by astrocytic glutamyl transpeptidase (GT) to the dipeptide cysteinylglycine (CysGly) and hydrolysis of this dipeptide by neuronal aminopeptidase N (ApN) to cysteine (Cys) and glycine (Gly)

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