Abstract Cell transfection efficiency is still a limiting factor in gene function research
The abnormal activation of this pathway leads to the downregulation of endothelial cell junction proteins (such as VE-cadherin and occludin) expression, disrupts the integrity of the endothelial barrier, increases pulmonary vascular permeability, and triggers pulmonary edema and acute lung injury
Its three amino acids enable it to act on: Cells: Protection against free radicals, DNA synthesis, and repair
10.1186/s12967-024-04853-0 217
Moreover, reactive oxygen species, which activate apoptotic pathways in cancer cells, may be generated by curcumin and it may also raise intracellular calcium levels, which help trigger apoptosis by altering the poetics of cell membranes