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10.1016/j.cell.2017.09.021 Cell 125 StyA.GalyB.StarzyskiR

In healthy mitochondria, SIRT3 interacts with ATP5O, while the low pH owing to the loss of membrane potential weakens the binding affinity between SIRT3 and ATP5O, leading to the redistribution of SIRT3 to other mitochondria substrates

Provides UV protection for the skin from the inside and reduces redness associated with sunburn

The pathogenesis of vitiligo may also be influenced by the emerging processes of regulated cell death known as ferroptosis, necroptosis and pyroptosis [25]

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