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Profiles of Drug Substances, Excipients and Related Methodology (2023)

Because S(+)KET has higher affinity for NMDA receptors than R()KET, S(+)KET has been developed and later approved by the Food and Drug Administration as a clinical antidepressant (Hashimoto, 2019)

To measure the effect of the paramagnetic label, 1 H, 15 N and 1 H, 13 C HSQC spectra with long inter-scan delays (3 s) of 100 M 13 C/ 15 N-labeled p53 TAD2 in presence of one stoichiometric equivalent paramagnetically labeled FOXO4 FH were recorded before and after addition of 5 mM ascorbic acid

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