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Medication overuse headache, sometimes called rebound headache, is a real phenomenon where taking pain relievers too frequently actually causes more headaches

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Similar effects on IL-1, IL-6, and IL-8 levels were observed when cells were treated with simvastatin, pravastatin, and the renin-angiotensin system inhibitors spironolactone, captopril, lisinopril, candesartan, and losartan

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Oral medications may reach full dose in 24 weeks