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Supporting this view, many anterograde tracing and immunohistochemistry studies, with the exception of two studies 38,39 , have consistently shown that axons in the intestinal mucosa closely approach enteroendocrine cells without establishing contacts 22,24,27,40,41,42,43,44

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This capacity positions exercise as an indispensable tool in obesity management, capable of yielding significant health benefits even with modest improvements in physical activity levels

Paudel et al., 2018