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Using the nose-to-brain route to overcome listed pharmacokinetic challenges will allow future studies to better elucidate the neuroprotective efficacy of mitochondria-targeted drugs on CNS

One magnetic resonance spectroscopy study suggested that abnormal cerebral glucose metabolism was correlated with abnormal values of N-acetyl-aspartate (NAA) normalized to creatine (NAA/Cr) in brain regions associated with cognition ( There are limitations to the current study

The sulfur-containing amino acids: An overview

Additionally, the arginine deiminase pathway is common in gut commensal bacteria such as Enterococcus , Streptococcus , Clostridium , Lactococcus , and Lactobacillus ( 43)

March, pp