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(5) I Miescher, J Rieber, M Calcagni, and J Buschmann (2023) In Vitro and In Vivo Effects of IGF-1 Delivery Strategies on Tendon Healing: A Review International Journal of Molecular Sciences, 2023 Jan 25, Volume 24 (Issue 3), Page 2370

Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules

This early research is what has driven ongoing interest in BPC-157 across scientific and wellness communities

These regulatory effects may underlie observed improvements in sleep-wake patterns and neuroendocrine homeostasis in aged subjects [3]

To overcome these barriers, advanced formulation strategies have been developed to enhance solubility, protect functional integrity, and achieve controlled, site-specific delivery (Chen et al., 2024) to support clinical translation (Aljabali et al., 2025)