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However, the gastrointestinal side effects commonly associated with GLP-1 receptor agonistssuch as nausea, vomiting, and diarrhoeacan lead to dehydration and prerenal acute kidney injury, particularly in patients whose renal reserve is already limited

This is where semaglutide can make a difference

Hepatobiliary: cholecystitis, cholecystectomy Neurologic: dysesthesia Pulmonary: Pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation

[1] If the solution is drawn into a syringe for injection, it should be administered promptly for the same reason (avoid leaving the filled syringe exposed to light for long)

Even treatments like Trulicity and Victoza fall into this category