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Tan DX, Reiter RJ, Manchester LC, Yan MT, El-Sawi M, Sainz RM, et al

Biguanides: species with versatile therapeutic applications

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As more younger adults are being treated with therapies that have been inadequately studied in pregnancy, it is essential to describe the reproductive safety of recommended approaches

If muscle pain is severe, persistent, or accompanied by weakness, dark urine, or significant functional impairment, seek urgent medical attention via NHS 111, your GP, or A&E as appropriate