(Cockcroft-Gault (C-G), Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)) are more correctly regarded as measures of serum creatinine and/or cystatin C that have been adjusted for age, gender, and race, then factored to produce a numerical quantity similar to a measured GFR
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You should contact your GP or healthcare provider if you notice: Lymph nodes that remain swollen for more than 3-6 weeks without obvious cause Nodes that are hard, fixed, or immobile rather than soft and moveable Progressive enlargement of lymph nodes over time Swollen nodes in multiple areas of the body simultaneously (generalised lymphadenopathy) Supraclavicular lymph nodes (above the collarbone) these are particularly concerning Nodes measuring more than 12 cm in diameter Lymph node swelling accompanied by unexplained weight loss Night sweats that soak your bedclothes Persistent fever without an obvious infection Difficulty breathing or swallowing if nodes are in the neck area Many of these features may warrant an urgent suspected cancer referral (two-week wait) as per NICE guidance
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