Along with truncating the C-terminal, this exposes exenatide to NEP 24.11 degradation
Very Common Side Effects of Mounjaro - Nausea - Diarrhoea or constipation - Vomiting - Low blood sugar (if combined with diabetes meds) Common Side Effects of Mounjaro - Indigestion or reflux - Bloating, gas, or burping - Low blood pressure - Hair loss - Fatigue - Injection site reactions Read our more in-depth guide on Mounjaro side effects Uncommon Side Effects of Mounjaro(Seek Medical Help if Severe) - Development of gallstones - An increase in heart rate - Pancreatitis (severe stomach pain) - Increased pancreatic enzyme levels (blood tests required) For a full list, check the Patient Information Leaflet
Call 911 or go to the emergency department immediately for : Severe shortness of breath, chest pain, or palpitations Signs of severe allergic reaction: swelling of face, lips, tongue, or throat
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In the SURPASS-2 head-to-head trial, tirzepatide produced nearly double the weight loss of semaglutide (15% vs 8% in T2D patients)