glutathione sulfur sensitivity Natural compounds in mental health and neurological disorders: insights from observational and intervention studies Sulfur partitioning from cysteine controls

doi:10.1001/jamanetworkopen.2022.36131 Mills EG, et al

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Some other factors like illnesses, chronic colds, pollution, smoking and inflammatory conditions also lead to excessive usage of glutathione and hence, its depletion

The connection between B12 and mental health is well-documented, with physicians recognizing the association between vitamin B12 deficiency and neuropsychiatric conditions

33 Oxidative stress is associated with the pathophysiology of cardiovascular diseases (CVDs), while antioxidants are involved in neutralizing ROS and protecting against oxidative stress