[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Open-label trial in Parkinson's disease (PD) (TEMPO-4) [ Apr
ZhangXLiYYangPLiuXLuLChenYet alTrimethylamine-N-Oxide promotes vascular calcification through activation of NLRP3 (Nucleotide-binding domain, leucine-rich-containing family, Pyrin Domain-Containing-3) Inflammasome and NF-B (Nuclear Factor B) signals
BPC 157 reduced levels of all necrosis markers, CK, CK-MB, LDH, and cTnT, and attenuated gross (no visible infarcted area) and histological damage, ECG (no ST-T ischemic changes), and echocardiography (preservation of systolic left ventricular function) damage induced by isoprenaline
JACC Heart Fail
It's worth being realistic here: Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals)