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Furthermore, VPA reduces the release of the epileptogenic -hydroxybutyric acid and attenuates the neuronal excitation induced by N -methyl-D-aspartate (NMDA)-type glutamate receptors [9]

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Curr Opin Immunol (2020) 62:5461

Zhang H, Lu M, Zhang X, Kuai Y, Mei Y, Tan Q, Zhong K, Sun X, Ta W (2019) Isosteviol sodium protects against ischemic stroke by modulating microglia/macrophage polarization via disruption of GAS5/miR-146a-5psponge

The control solution (30L) and the test solution (5mL) was pipeted to brown volumetric flask respectively, and 30L of 0.05mol / L carbonate buffer (pH = 10.3), 1 00ul of pyridine acetonitrile solution (each 1ml acetonitrile contained pyridine 5ul) and 100L of 0.5% derivatization reagent was added respectively and mixed