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C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation

BSO reduces GSH pools to below 1% in many cell types 25,26 and is generally well tolerated, including in studies on other intracellular bacteria where it was used at millimolar concentrations 15,17

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541 The BBB controls the entry of circulating substances and cells into the brain, maintaining the stability of normal brain function and serving as the primary barrier for iron entry