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N Engl J Med (2011) 364:82941

In clinical research, dose escalation and monitoring rules are set by a study protocol

doi: 10.17582/JOURNAL.PJZ/20200429100456 Pak J Zool 199

In this sense, Met plays a fundamental role in the liver by stimulating the synthesis of very low-density lipoprotein (VLDL), and therefore, helps reduce TAG accumulation (Martinov et al., 2010)