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Similarly to other drug metabolising enzymes, UGTs are subject to induction by various xenobiotics or biologically active endogenous compounds (hormones) via nuclear receptors and transcription factors

Glutathione S-transferase (GST, EC 2.5.1.18) activity Glutathione S-transferase (GST) activity was determined by following the formation of dinitrobenzene glutathione thioether complex formed by the conjugation of GSH with 1-chloro 2,4- dinitrobenzene (CDNB) (18)

Lemmens SG, Martens EA, Kester AD, Westerterp-Plantenga MS

[16] Elevated levels following injection may persist for up to two weeks and should be considered when interpreting test results

In addition to the above findings, several studies have shown that GLP-1RA therapy results in larger proportions of patients achieving 5% and 10% body weight loss than with placebo (Table 1)