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For individuals with alcohol use disorder specifically, additional safety considerations arise

Clinical studies show that approximately 50% to 70% of lost weight is regained within a year of discontinuation, which underscores the challenge of achieving lasting results

As research continues to elucidate additional mechanisms and clinical applications, the therapeutic scope of GLP-1RAs is expected to further diversify.[21] This review summarizes emerging and established evidence on the use of GLP-1RAs beyond glycemic control in diabetes, highlighting current indications, investigational uses, and future directions for this evolving class of agents

Tirzepatide versus Semaglutide once Weekly in patients with type 2 diabetes

doi: 10.3389/fmed.2021.735150