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Data Availability Statement The original contributions presented in this study are included in the article/Supplementary Material

The unfolded protein response (UPR) is triggered when an excessive amount of misfolded proteins accumulate in the ER, which can be caused by overnutrition, increased reactive oxygen species (ROS), or proinflammatory cytokines (24, 25)

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How Long It Realistically Takes to See Results Understanding timelines helps set realistic expectations and avoid frustration: Week 12: Skin is adjusting

448 In summary, acetazolamide appears to be an efficient and safe option for chronic CMS treatment, although its long-term effects need to be further addressed