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Food and Drug Administration for weight loss, for people with a BMI of at least 35

Theres no clear indication of safety measures

If left untreated, obesity can lead to a range of serious health conditions, including Type 2 diabetes, high blood pressure and cholesterol, heart disease, sleep apnea, osteoarthritis, and cancer

[Google Scholar] 26.Weghuber D, Barrett T, Barrientos-Prez M, Gies I, Hesse D, Jeppesen OK, Kelly AS, Mastrandrea LD, Srrig R, Arslanian S STEP TEENS Investigators

Nystrom T: The potential beneficial role of glucagon-like peptide-1 in endothelial dysfunction and heart failure associated with insulin resistance