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When melanotan binds to the MC-1 receptor, it stimulates the body to increase the production of melanin, the substance in the skin that gives it its pigment

Cumulus oocyte complexes (COCs) were aspirated from antral follicles with a diameter of 38 mm using an 18-gauge needle and a disposable 10-mL syringe from the ovarian cortex and the obtained cumulus oocyte complexes within oocyte washing medium (BO-Wash, IVF Bioscience) evaluated under a stereomicroscope according to the quality criteria established 70

There were indications of enhanced mitochondrial membrane potential and increased mtDNA copy numbers, suggesting that Epithalon might support mitochondrial integrity and functionality as oocytes age

doi: 10.2337/db13-0639 202