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Our providers came to Innovative from several area hospitals, including Northwestern, Illinois Masonic, Rush, University of Chicago, and Loyola

By encapsulating drug molecules in nanoparticles, nanoparticle drug delivery systems exhibit the advantage of improved drug loading, less exposure of the drug molecule to metabolic enzymes and drug efflux pumps, longer blood circulation, and facilitation of drug passage through the cell membrane via transcytosis instead of passive diffusion

We did not include other standard treatments, such as all kinds of chemotherapies and radiotherapies, as these therapies cause random and widespread DNA damage, which might confound the identification of specific key mechanisms

While more rigid clinical controls are obviously needed for long-term study, these early observations point to optimistic outcomes for GLP-1s being successfully used for substance abuse treatment

The platform does not compound or customize dosing, limiting formulation flexibility compared to dedicated compounding models