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Unlike crash diets or extreme calorie restriction, these medications work by regulating hunger hormones to reduce cravings and help you feel full longer on a healthy, nutrient-dense dietmaking it easier to adopt long-term healthy habits

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GIP is glucose-dependent insulinotropic polypeptide, another incretin hormone involved in post-meal insulin response

All participants who regained 50% of their body weight from SURMOUNT-5 were treated with rescue orforglipron therapy

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