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Alternative treatment for the underlying medical condition should be initiated as clinically indicated [see Warnings and Precautions (5.5)]

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Molecular biology of amyotrophic lateral sclerosis: insights from genetics

In addition, the p62-Keap1-NRF2 32 , ATG5-ATG7-NCOA4 33 , and glutamine metabolic pathways 25 can effectively regulate the formation of intracellular iron ions and ROS and play a regulatory role in ferroptosis (Fig

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