The precise delivery and stability of these peptides are crucial, as they must remain intact and functional upon reaching the epidermis and dermis
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The combination of DNase-I + amikacin resulted in a strong increase in dead biofilm compared to DNase I treatment alone, and the triple therapy combination of GSH + DNase-I + amikacin showed the highest level of biofilm disruption (Figure 3C)
Specifically, the deletion of TrkB in iSPNs elevated the expression of Gsto2 , thereby leading to increased dopamine levels through alterations of ascorbic acid homeostasis and disruption of energy metabolism in the neurons
International Journal of Endocrinology, 2020 , 7850816