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This could be attributed to the different mechanisms of action of these two drugs

J Biol Chem 284:1896318971 Tolin S, Arrigoni G, Trentin AR, Veljovic-Jovanovic S, Pivato M, Zechman B, Masi A (2013) Biochemical and quantitative proteomics investigations in Arabidopsis ggt1 mutant leaves reveal a role for the gamma-glutamyl cycle in plants adaptation to environment

A single therapeutic agent, no matter how potent, may not address all underlying issues comprehensively

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The water drinkers were also about twice as likely to achieve diabetes remission