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5 While its primary endpoint (a composite including all-cause mortality, nonfatal MI, stroke, acute coronary syndrome, leg revascularization, and major leg amputation) did not reach significance, a main secondary composite endpoint (all-cause mortality, nonfatal MI, and stroke) showed a significant benefit with pioglitazone (hazard ratio [HR] 0.84

These tests include blood pressure readings, blood glucose measurements, lipid profile, and kidney and liver function tests

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