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The study was approved by the Ethics Committee of Helsinki and Uusimaa Hospital District and conducted according to the declaration of Helsinki, and the study subjects gave informed consent

According to the manufacturers of Ozempic and Wegovy, the main common side effects may include: Nausea, vomiting, and diarrhea that could lead to an acute kidney injury Dizziness Rapid heart rate Headaches Hypoglycemia Allergic reactions to the medication Abdominal pain Shortness of breath Severe hypoglycemia Blurred vision Severe rash Slurred speech Hoarse voice Other minor side effects to watch out for include a rise in resting heart rate, a decrease in heart rate variability, and mood changes (like anxiety and depression)

If you are experiencing active vomiting or diarrhea from your weight loss medication, avoid taking naproxen until your symptoms subside and you are rehydrated

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Possible reasons include the longer treatment duration in TRIUMPH-4 (68 vs 40 weeks), differences in how symptoms were captured, and differences in patient populations