moderate amounts when applied topically can be safe
Thymosin beta-4 was studied in animal and cell experiments for roles in cell migration, angiogenesis and softtissue repair, with TB-500 assumed to behave similarly rather than being independently validated
There is also an increased sensitization of the excitatory neurotransmitter system, such as NMDA glutamate receptors, the reduction in the number of GABA receptors (downregulation), the shift of benzodiazepine receptors to an inverse agonist state, and compensatory changes in other components of the macromolecular GABA/benzodiazepine/chloride ionophore complex (for review see, i.e., [219,220,221,222,223,224,225])
It is well-studied for its role in tissue regeneration
What Makes Sublingual Peptides Different