These are less common in primary care but appear in hematology and emergency settings
In addition, consistent with the findings reported elsewhere, we found DMF induces the activation of NRF2, and NRF2 targets such as those involved in cystine uptake (SLC7A11) and GSH biosynthesis (GCLM and GCLC, the mediator and catalytic subunits of GCL) (Fig
Pharmacologically induced slowing of gastric emptying by GLP1RAs should be considered in patients treated with short-acting insulin for appropriate timing of administration of the insulin drug and probable use of rapid rather than ultra-rapid insulin analogues
For patients with known asymptomatic gallstones who are about to start high-dose GLP-1 therapy, the balance is different and pre-emptive surgery may be reasonable
When comparing Januvia vs Ozempic, the differences are significant: Ozempic (semaglutide) crushes Januvia (sitagliptin) for weight loss achieving up to 15% body weight reduction compared to Januvias modest 2 to 4 pounds but Januvia remains substantially cheaper and causes virtually no gastrointestinal side effects