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Reilly AM, Harris PJ, Williams DA

Pediatric patients who suddenly develop OCD, vocal or motor tics, rage episodes, separation anxiety, or behavioral regression, particularly following an infection, should be evaluated for PANS/PANDAS and mast cell activation

Mitochondrial fission is regulated mainly by cytoplasmic DRP1, fission1 (FIS1), and mitochondrial fission factor (MFF) (Zhou et al., 2020)

Negative findings of a direct antiglobulin test will militate against autoimmune hemolytic anemia

FOXO4-DRI is a large peptide (~5382 Da, 48 amino acids) with a critical structural modification: the D-Retro-Inverso (DRI) design uses D-amino acids in reversed sequence to confer protease resistance while maintaining the 3D spatial arrangement needed for target binding