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In a randomized controlled trial assessing the effects of butyrate in obese children, there was a consistent response which showed a significant reduction of bodyweight and waist circumference compared to placebo [4]. Per-protocol analysis in the butryate group revealed a decrease in BMI of 2.26 units and a reduction in waist circumference by 5.07cm in 6 months [4]

While there is a growing body of preclinical research suggesting metabolic benefits, robust human clinical trials particularly large-scale, randomised controlled trials (RCTs) are largely absent

The bacteriostatic properties of the water are particularly valuable for NAD+ research given the compounds relatively high per-dose volumes

Your prescriber makes that call

Your physician evaluates your health profile, current medications, and treatment goals to determine whether combination therapy is appropriate