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Lifestyle changes, such as a healthy diet and regular exercise, are important for anyone taking weight loss medication

However, most side effects were manageable, resolved over time, and did not lead to participants dropping out of the trial

In a foundational 2009 study, Li and colleagues found that GLP-1R stimulation preserved both cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism [5]

The label recommends reducing the dose from 5 mg twice daily to 2.5 mg twice daily when co-administered with these agents, except in patients already on 2.5 mg for age, weight, or creatinine criteria

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