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And because of the one-week half-life of semaglutide products, the symptoms could last a while, requiring a prolonged observation period, the FDA said

By controlling hunger and reducing overall food intake, it can help patients lose an average of 10-15% of their body weight in the first year

To date, two incretin hormones have been discovered: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) [2]

Rodrguez-Baeza, I

Because it provides a constant level of insulin regardless of blood sugar status, blood glucose can drop dangerously low if a patient skips meals, exercises vigorously, or takes too much insulin