New England Journal of Medicine , 2022;387(3):205-216
Ophiopogon japonicus polysaccharide (OJP) inhibited DOX-induced myocardial ferroptosis through activation of the Nrf2/GPX4 pathway, reduced LDH, CK-MB as well as cTn-I levels, and enhanced ATP generation, hence alleviated myocardial toxicity ( Polygonatum odoratum polysaccharides (POP) activated the Nrf2/HO-1 pathway to inhibit ferroptosis and alleviated cisplatin-induced acute kidney injury ( Aconitum carmichaelii (RFP) had the cytotoxicity effects on hydrogen peroxide-induced injury and prohibited apoptosis in vitro, by contrast, RFP attenuated cisplatin-induced acute kidney injury in vivo through inhibition of ferroptosis with the increased levels of GSH and GPX4, the decreased levels of MDA and 4-hydroxynonenal as well as the reduced lipid peroxidation (Tian et al., 2022)
Taylor RC, Cullen SP, Martin SJ
I have never been anxious about receiving an injection, but I must admit that in the beginning the thought of giving myself one was a bit strange
Lightening the skin was an accidental discovery
