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No participants developed anti-AOD-9604 antibodies in the subset tested, and no statistically significant changes in IGF-1 or vital signs were seen

10.3390/antiox13111402 43 JungM.KasamatsuS.MatsunagaT.AkashiS.OnoK.NishimuraA.et al (2016)

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The free energy corrections were considered at the temperature of 298 K, following: where E, GZPE, GU, and S refer to the DFT calculated energy change, the correction from zero-point energy, the correction from inner energy, and the correction from entropy 63